Leggy A. Arnold: search on Z-Library

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1

Highly Enantioselective Copper-Catalyzed Allylic Alkylation with Phosphoramidite Ligands

Anthoni W. van Zijl, Leggy A. Arnold, Adriaan J. Minnaard, Ben L. Feringa

Journal:

Advanced Synthesis & Catalysis

Year:

2004

Language:

english

File:

PDF, 171 KB

english, 2004

2

Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites

Teske, Kelly A., Bogart, Jonathon W., Sanchez, Luis M., Yu, Olivia B., Preston, Joshua V., Cook, James M., Silvaggi, Nicholas R., Bikle, Daniel D., Arnold, Leggy A.

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 802 KB

english, 2016

3

A New Pharmacological Approach for Asthma through Tissue-Specific Modulation of the GABA(A) Receptor

Arnold, Leggy A., Forkuo, Gloria S., Nieman, Amanda N., Yu, Olivia B., Guthrie, Margaret L., Yuan, Nina Y., Kodali, Revathi, Jahan, Rajwana, Emala, Charles W., Cook, James M., Stafford, Douglas C., Gr

Journal:

Journal of Allergy and Clinical Immunology

Year:

2016

Language:

english

File:

PDF, 123 KB

english, 2016

4

Highly Enantioselective Copper–Phosphoramidite Catalyzed Kinetic Resolution of Chiral 2-Cyclohexenones

Robert Naasz, Leggy A. Arnold, Adriaan J. Minnaard, Ben L. Feringa

Journal:

Angewandte Chemie

Year:

2001

Language:

english

File:

PDF, 95 KB

english, 2001

5

Highly Enantioselective Copper–Phosphoramidite Catalyzed Kinetic Resolution of Chiral 2-Cyclohexenones

Robert Naasz, Leggy A. Arnold, Adriaan J. Minnaard, Ben L. Feringa

Journal:

Angewandte Chemie International Edition

Year:

2001

Language:

english

File:

PDF, 95 KB

english, 2001

6

Hochenantioselektive katalytische 1,4-Addition und kombinierte 1,4-Addition/Aldolreaktion von Organozinkreagentien an Enone

Prof. Dr. Ben L. Feringa, Dr. Mauro Pineschi, Leggy A. Arnold, Rosalinde Imbos, André H. M. De Vries

Journal:

Angewandte Chemie

Year:

1997

File:

PDF, 487 KB

1997

7

Highly Enantioselective Catalytic Conjugate Addition and Tandem Conjugate Addition–Aldol Reactions of Organozinc Reagents

Prof. Dr. Ben L. Feringa, Dr. Mauro Pineschi, Leggy A. Arnold, Rosalinde Imbos, André H. M. de Vries

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 521 KB

english, 1997

8

ChemInform Abstract: Catalytic Enantioselective Annulations via 1,4-Addition—Aldol Cyclization of Functionalized Organozinc Reagents.

Robert Naasz, Leggy A. Arnold, Mauro Pineschi, Erik Keller, Ben L. Feringa

Journal:

Year:

1999

File:

PDF, 32 KB

1999

9

ChemInform Abstract: Enantioselective Catalytic Conjugate Addition of Dialkylzinc Reagents Using Copper—Phosphoramidite Complexes; Ligand Variation and Non-linear Effects.

Leggy A. Arnold, Rosalinde Imbos, Alessandro Mandoli, Andre H. M. de Vries, Robert Naasz, Ben L. Feringa

Journal:

Year:

2001

File:

PDF, 33 KB

2001

10

ChemInform Abstract: Highly Enantioselective Copper-Phosphoramidite Catalyzed Kinetic Resolution of Chiral 2-Cyclohexenones.

Robert Naasz, Leggy A. Arnold, Adriaan J. Minnaard, Ben L. Feringa

Journal:

Year:

2001

File:

PDF, 35 KB

2001

11

ChemInform Abstract: Enantioselective Copper-Catalyzed Allylic Alkylation with Dialkylzincs Using Phosphoramidite Ligands.

Hinke Malda, Anthoni W. van Zijl, Leggy A. Arnold, Ben L. Feringa

Journal:

Year:

2001

File:

PDF, 35 KB

2001

12

ChemInform Abstract: Enantioselective Synthesis of Bicyclic Compounds via Catalytic 1,4-Addition-Ring Closing Metathesis.

Robert Naasz, Leggy A. Arnold, Adriaan J. Minnaard, Ben L. Feringa

Journal:

Year:

2001

File:

PDF, 30 KB

2001

13

ChemInform Abstract: Catalytic Enantioselective Synthesis of Prostaglandin E1 Methyl Ester Using a Tandem 1,4-Addition—Aldol Reaction to a Cyclopentene-3,5-dione Monoacetal.

Leggy A. Arnold, Robert Naasz, Adriaan J. Minnaard, Ben L. Feringa

Journal:

Year:

2001

File:

PDF, 37 KB

2001

14

ChemInform Abstract: New Bidentate Chiral Phosphoramidites in Copper-Catalyzed Asymmetric 1,4-Addition of Diethylzinc to Cyclic α,β-Enones: Enantioselective Tandem 1,4-Addition-Aldol Reactions with 2-Cyclopentenone.

Alessandro Mandoli, Leggy A. Arnold, Andre H. M. de Vries, Piero Salvadori, Ben L. Feringa

Journal:

Year:

2002

File:

PDF, 32 KB

2002

15

Copper Phosphoramidite Catalyzed Enantioselective Ring-Opening of Oxabicyclic Alkenes: Remarkable Reversal of Stereocontrol.

Fabio Bertozzi, Mauro Pineschi, Franco Macchia, Leggy A. Arnold, Adriaan J. Minnaard, Ben L. Feringa

Journal:

Year:

2002

File:

PDF, 33 KB

2002

16

Synthesis of Medium Ring Heterocycles Using an Intramolecular Heck Reaction.

Leggy A. Arnold, Wenchen Luo, R. Kiplin Guy

Journal:

Year:

2004

File:

PDF, 34 KB

2004

17

Synthesis of highly substituted dibenzo[b,f]azocines and their evaluation as protein kinase inhibitors

Leggy A. Arnold, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 163 KB

english, 2006

18

Synthesis and characterization of BODIPY-labeled colchicine

Leggy A. Arnold, Patricia Ranaivo, R. Kiplin Guy

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

19

Enantioselective Catalytic Conjugate Addition of Dialkylzinc Reagents using Copper–Phosphoramidite Complexes; Ligand Variation and Non-linear Effects

Leggy A Arnold, Rosalinde Imbos, Alessandro Mandoli, André H.M de Vries, Robert Naasz, Ben L Feringa

Journal:

Year:

2000

Language:

english

File:

PDF, 315 KB

english, 2000

20

New bidentate chiral phosphoramidites in copper-catalyzed asymmetric 1,4-addition of diethylzinc to cyclic α,β-enones: enantioselective tandem 1,4-addition-aldol reactions with 2-cyclopentenone

Alessandro Mandoli, Leggy A Arnold, Andre H.M de Vries, Piero Salvadori, Ben L Feringa

Journal:

Tetrahedron: Asymmetry

Year:

2001

Language:

english

File:

PDF, 118 KB

english, 2001

21

Inhibition of a viral enzyme by a small-molecule dimer disruptor

Shahian, Tina, Lee, Gregory M, Lazic, Ana, Arnold, Leggy A, Velusamy, Priya, Roels, Christina M, Guy, R Kiplin, Craik, Charles S

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 891 KB

english, 2009

22

Inhibitors of the Interaction of a Thyroid Hormone Receptor and Coactivators: Preliminary Structure−Activity Relationships

Arnold, Leggy A., Kosinski, Aaron, Estébanez-Perpiñá, Eva, Guy, R. Kiplin

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

23

An Integrated In Vitro and In Vivo High-Throughput Screen Identifies Treatment Leads for Ependymoma

Jennifer M. Atkinson, Anang A. Shelat, Angel Montero Carcaboso, Tanya A. Kranenburg, Leggy A. Arnold, Nidal Boulos, Karen Wright, Robert A. Johnson, Helen Poppleton, Kumarasamypet M. Mohankumar, Cleme

Journal:

Year:

2011

Language:

english

File:

PDF, 4.26 MB

english, 2011

24

Evaluation of the first Ergocalciferol-derived, non hypercalcemic anti-cancer agent MT19c in ovarian cancer SKOV-3 cell lines

Laurent Brard, Thilo S. Lange, Katina Robison, Kyu Kwang Kim, Tahniyath Ara, Megan Marie McCallum, Leggy A. Arnold, Richard G. Moore, Rakesh K. Singh

Journal:

Gynecologic Oncology

Year:

2011

Language:

english

File:

PDF, 1.77 MB

english, 2011

25

Discovery of the First Irreversible Small Molecule Inhibitors of the Interaction between the Vitamin D Receptor and Coactivators

Nandhikonda, Premchendar, Lynt, Wen Z., McCallum, Megan M., Ara, Tahniyath, Baranowski, Athena M., Yuan, Nina Y., Pearson, Dana, Bikle, Daniel D., Guy, R. Kiplin, Arnold, Leggy A.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

26

Catalytic Enantioselective Synthesis of Prostaglandin E 1 Methyl Ester Using a Tandem 1,4-Addition-Aldol Reaction to a Cyclopenten-3,5-dione Monoacetal

Arnold, Leggy A., Naasz, Robert, Minnaard, Adriaan J., Feringa, Ben L.

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 45 KB

english, 2001

27

Similarities and Differences between Two Modes of Antagonism of the Thyroid Hormone Receptor

Sadana, Prabodh, Hwang, Jong Yeon, Attia, Ramy R., Arnold, Leggy A., Neale, Geoffrey, Guy, R. Kiplin

Journal:

ACS Chemical Biology

Year:

2011

Language:

english

File:

PDF, 3.86 MB

english, 2011

28

A fluorescence-based high throughput assay for the determination of small molecule−human serum albumin protein binding

McCallum, Megan M., Pawlak, Alan J., Shadrick, William R., Simeonov, Anton, Jadhav, Ajit, Yasgar, Adam, Maloney, David J., Arnold, Leggy A.

Journal:

Analytical and Bioanalytical Chemistry

Year:

2014

Language:

english

File:

PDF, 596 KB

english, 2014

29

Copper Phosphoramidite Catalyzed Enantioselective Ring-Opening of Oxabicyclic Alkenes: Remarkable Reversal of Stereocontrol

Bertozzi, Fabio, Pineschi, Mauro, Macchia, Franco, Arnold, Leggy A., Minnaard, Adriaan J., Feringa, Ben L.

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 50 KB

english, 2002

30

Enantioselective Copper-Catalyzed Allylic Alkylation with Dialkylzincs Using Phosphoramidite Ligands

Malda, Hinke, van Zijl, Anthoni W., Arnold, Leggy A., Feringa, Ben L.

Journal:

Organic Letters

Year:

2001

Language:

english

File:

PDF, 46 KB

english, 2001

31

Improvement of Pharmacological Properties of Irreversible Thyroid Receptor Coactivator Binding Inhibitors

Hwang, Jong Yeon, Arnold, Leggy A., Zhu, Fangyi, Kosinski, Aaron, Mangano, Thomas J., Setola, Vincent, Roth, Bryan L., Guy, R. Kiplin

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

32

Novel Flufenamic Acid Analogues as Inhibitors of Androgen Receptor Mediated Transcription

Féau, Clémentine, Arnold, Leggy A., Kosinski, Aaron, Zhu, Fangyi, Connelly, Michele, Guy, R. Kiplin

Journal:

ACS Chemical Biology

Year:

2009

Language:

english

File:

PDF, 1.73 MB

english, 2009

33

Synthesis of Medium Ring Heterocycles Using an Intramolecular Heck Reaction

Arnold, Leggy A., Luo, Wenchen, Guy, R. Kiplin

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 53 KB

english, 2004

34

Catalytic Enantioselective Synthesis of (−)-Prostaglandin E 1 Methyl Ester Based on a Tandem 1,4-Addition−Aldol Reaction

Arnold, Leggy A., Naasz, Robert, Minnaard, Adriaan J., Feringa, Ben L.

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 239 KB

english, 2002

35

Glo1 inhibitors for neuropsychiatric and anti-epileptic drug development

McMurray, Katherine M.J., Distler, Margaret G., Sidhu, Preetpal S., Cook, James M., Arnold, Leggy A., Palmer, Abraham A., Plant, Leigh D.

Journal:

Biochemical Society Transactions

Year:

2014

Language:

english

File:

PDF, 547 KB

english, 2014

36

Catalytic Enantioselective Annulations via 1,4-Addition−Aldol Cyclization of Functionalized Organozinc Reagents

Naasz, Robert, Arnold, Leggy A., Pineschi, Mauro, Keller, Erik, Feringa, Ben L.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 69 KB

english, 1999

37

Quantification of the Vitamin D Receptor−Coregulator Interaction †

Teichert, Arnaud, Arnold, Leggy A., Otieno, Steve, Oda, Yuko, Augustinaite, Indre, Geistlinger, Tim R., Kriwacki, Richard W., Guy, R. Kiplin, Bikle, Daniel D.

Journal:

Year:

2009

Language:

english

File:

PDF, 4.08 MB

english, 2009

38

Development of Novel Vitamin D Receptor–Coactivator Inhibitors

Sidhu, Preetpal S., Nassif, Nicholas, McCallum, Megan M., Teske, Kelly, Feleke, Belaynesh, Yuan, Nina Y., Nandhikonda, Premchendar, Cook, James M., Singh, Rakesh K., Bikle, Daniel D., Arnold, Leggy A.

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 740 KB

english, 2014

39

Catalytic Enantioselective Synthesis of Prostaglandin E 1 Methyl Ester Using a Tandem 1,4-Addition-Aldol Reaction to a Cyclopenten-3,5-dione Monoacetal

Arnold, Leggy A., Naasz, Robert, Minnaard, Adriaan J., Feringa, Ben L.

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 36 KB

english, 2001

40

Enantioselective synthesis of bicyclic compounds via catalytic 1,4-addition-ring closing metathesis

Naasz, Robert, Arnold, Leggy A., Minnaard, Adriaan J., Feringa, Ben L.

Journal:

Chemical Communications

Year:

2001

Language:

english

File:

PDF, 42 KB

english, 2001

41

Comparison of Cell Expression Formats for the Characterization of GABA A Channels Using a Microfluidic Patch Clamp System

Chen, Qin, Yim, Peter D., Yuan, Nina, Johnson, Juliette, Cook, James M., Smith, Steve, Ionescu-Zanetti, Cristian, Wang, Zhi-Jian, Arnold, Leggy A., Emala, Charles W.

Journal:

Assay and Drug Development Technologies

Year:

2012

Language:

english

File:

PDF, 688 KB

english, 2012

42

Structural Insight into the Mode of Action of a Direct Inhibitor of Coregulator Binding to the Thyroid Hormone Receptor

Estébanez-Perpiñá, Eva, Arnold, Leggy A., Jouravel, Natalia, Togashi, Marie, Blethrow, Justin, Mar, Ellena, Nguyen, Phuong, Phillips, Kevin J., Baxter, John D., Webb, Paul, Guy, R. Kiplin, Fletterick,

Journal:

Molecular Endocrinology

Year:

2007

Language:

english

File:

PDF, 479 KB

english, 2007

43

Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice

McMurray, Katherine M. J., Sidhu, Preetpal S., Cook, James M., Arnold, Leggy A., Palmer, Abraham A.

Journal:

Addiction Biology

Year:

2015

Language:

english

File:

PDF, 706 KB

english, 2015

44

Calcitroic acid – a review

Yu, Olivia B., Arnold, Leggy A.

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 4.00 MB

english, 2016

45

Characterization of GABAA receptor ligands with automated patch-clamp using human neurons derived from pluripotent stem cells

Yuan, Nina Y., Poe, Michael M., Witzigmann, Christopher, Cook, James M., Stafford, Douglas, Arnold, Leggy A.

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2016

Language:

english

File:

PDF, 628 KB

english, 2016

46

Synthesis and characterization of a novel gamma-aminobutyric acid type A (GABA A ) receptor ligand that combines outstanding metabolic stability, pharmacokinetics, and anxiolytic efficacy

Poe, Michael M., Methuku, Kashi Reddy, Li, Guanguan, Verma, Ashwini R., Teske, Kelly A., Stafford, Douglas C., Arnold, Leggy A., Cramer, Jeffrey W., Jones, Timothy M., Cerne, Rok, Krambis, Michael J.,

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 511 KB

english, 2016

47

Pharmacological and antihyperalgesic properties of the novel α2/3 preferring GABA A receptor ligand MP-III-024

Fischer, Bradford D., Schlitt, Raymond J., Hamade, Bryan Z., Rehman, Sabah, Ernst, Margot, Poe, Michael M., Li, Guanguan, Kodali, Revathi, Arnold, Leggy A., Cook, James M.

Journal:

Brain Research Bulletin

Year:

2017

Language:

english

File:

PDF, 758 KB

english, 2017

48

Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells

Wang, Yibin, Fan, Heli, Balakrishnan, Kumudha, Lin, Zechao, Cao, Sheng, Chen, Wenbing, Fan, Yukai, Guthrie, Quibria A., Sun, Huabing, Teske, Kelly A., Gandhi, Varsha, Arnold, Leggy A., Peng, Xiaohua

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 997 KB

english, 2017

49

New Oral Treatments for Asthma through Tissue-Specific Modulation of the GABAA Receptor

Arnold, Leggy, Forkuo, Gloria, Nieman, Amanda, Yu, Olivia B., Guthrie, Margaret L., Kodali, Revathi, Yuan, Nina, Jahan, Rajwana, Stephen, Michael S., Emala, Charles W., Yocum, Gene T., Cook, James M.,

Journal:

Journal of Allergy and Clinical Immunology

Year:

2017

Language:

english

File:

PDF, 50 KB

english, 2017

50

A parallel chemistry approach to identify novel nuclear receptor ligands based on the GW0742 scaffold

Teske, Kelly A., Rai, Ganesha, Nandhikonda, Premchendar, Sidhu, Preetpal, Feleke, Belaynesh D., Simeonov, Anton, Yasgar, Adam, Jadhav, Ajit, Maloney, David J., Arnold, Leggy A.

Journal:

ACS Combinatorial Science

Year:

2017

Language:

english

File:

PDF, 821 KB

english, 2017

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